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NCLEX Medication Review: Top Medications to Know

As a nursing student, mastering common medications is essential. This is not only for safe patient care but also for passing the NCLEX exam. This review provides a quick review of the most frequently encountered drugs in nursing practice, including their uses, key nursing considerations, and potential side effects.

Albuterol

Purpose: Albuterol is a fast-acting bronchodilator used to open up the airways.

Uses:

  • Asthma
  • Chronic obstructive pulmonary disease (COPD)

Key Nursing Tips:

  • Always administer before corticosteroids to allow medication to reach the lungs effectively.
  • Monitor for increased heart rate, tremors, and nervousness, which are common side effects.

Digoxin

Purpose: Digoxin strengthens heart contractions while slowing the heart rate.

Uses:

  • Heart failure
  • Atrial fibrillation

Nursing Considerations:

  • Check the apical pulse for 1 full minute before administration; hold if <60 bpm in adults
  • Monitor potassium levels, as hypokalemia increases the risk of toxicity
  • Signs of toxicity include vision changes, nausea, and vomiting
  • Therapeutic range: 0.5–2 ng/mL
  • Antidote: Digibind

Furosemide (Lasix)

Purpose: Furosemide is a loop diuretic that removes excess fluid via the kidneys.

Uses:

  • Fluid overload in heart failure
  • Hypertension

Key Nursing Tips:

  • Monitor potassium levels to prevent hypokalemia; consider supplements or potassium-rich foods.
  • Administer IV slowly to avoid ototoxicity.

Pharmacology NCLEX Review

Heparin

Purpose: Heparin prevents clot formation by slowing the blood’s clotting ability.

Uses:

  • Pulmonary embolism (PE)
  • Deep vein thrombosis (DVT)
  • Atrial fibrillation

Nursing Considerations:

  • Monitor aPTT (target: 1.5–2.5 × normal).
  • Watch for excessive bleeding and heparin-induced thrombocytopenia (falling platelet counts).
  • Antidote: Protamine sulfate.

Insulin

Insulin helps regulate blood glucose levels. There are different types:

Regular Insulin

  • Onset: 30–60 minutes
  • Peak: 2–5 hours
  • Uses: Type 1 & 2 diabetes, diabetic ketoacidosis (DKA), hyperkalemia
  • Nursing Tip: Only insulin approved for IV use. When mixing with NPH insulin, draw regular insulin first (“clear to cloudy” or RN = Regular → NPH).

Glargine (Long-Acting)

  • Provides 24-hour glucose control
  • No peak
  • Do not mix with other insulins

Levothyroxine

Purpose: Thyroid hormone replacement for hypothyroidism

Nursing Tips:

  • Administer in the morning on an empty stomach
  • Monitor TSH and T4 levels

Lisinopril

Purpose: ACE inhibitor used to lower blood pressure

Uses:

  • Hypertension
  • Heart failure
  • Nursing Considerations:
  • Monitor for dry cough, which is common but bothersome.
  • Watch for angioedema and hyperkalemia.

Metformin

Purpose: Improves insulin sensitivity in patients with type 2 diabetes

Key Points:

  • Hold before and after contrast procedures (~48 hours).
  • Risk of lactic acidosis in patients with liver or kidney disease.

Metoprolol

Purpose: Beta-blocker that reduces heart rate and cardiac workload

Uses:

  • Heart failure
  • Hypertension
  • Arrhythmias

Nursing Considerations:

  • Hold if HR <60 bpm or SBP <100 mmHg.
  • Can mask hypoglycemia symptoms in diabetic patients (tachycardia, tremors).

Warfarin

Purpose: Anticoagulant that blocks vitamin K-dependent clotting factors

Uses:

  • DVT
  • PE
  • Atrial fibrillation

Nursing Tips:

  • Monitor INR (goal: 2–3).
  • Antidote: Vitamin K
  • Educate patients to avoid vitamin K-rich foods and watch for excessive bleeding.

Cheat Sheet for Top Medications to Know as a Nurse and on NCLEX

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