Registered Nurse RN

Registered Nurse, Free Care Plans, Free NCLEX Review, Nurse Salary, and much more. Join the nursing revolution.

  • RN
    • Nursing Clinical Skills
  • Nursing Videos
  • Blog
  • Nursing School
  • Nursing Care Plans
  • Nursing Quizzes
  • Nursing
  • Nursing Jobs
  • NCLEX Review
  • Store

Ladin’s Sign (Early Pregnancy Sign) Nursing Maternity Review

For nursing maternity exams, you want to be familiar with the early signs of pregnancy. This review will cover Ladin’s Sign.

To access more free nursing reviews, check out our maternity nursing videos.

What Is Ladin Sign?

Ladin sign is a probable sign of pregnancy that occurs around 6 weeks of gestation. It refers to a softening of the anterior midline portion of the uterus near the uterocervical junction.

The sign is named after Dr. Louis Ladin.

Key Features of Ladin Sign

ladin's sign, early pregnancy sign, signs of pregnancy, nclex, maternity nursing, ob nursing
Credit: RegisteredNurseRN.com
  • Occurs at approximately 6 weeks of pregnancy
  • Characterized by a soft, compressible area on the anterior uterus
  • Detected during a bimanual pelvic examination

Caused by:

  • Increased vascularization
  • Hormonal changes during pregnancy
  • Softening of uterine tissues

Why It Happens

During early pregnancy, increased blood flow and hormonal stimulation cause the uterus to become softer and more elastic. This softening creates the characteristic area felt during the pelvic exam.

Type of Pregnancy Sign

Ladin sign is classified as a:

  • Probable Sign of Pregnancy
  • This means the finding suggests pregnancy, but it is not definitive because similar uterine changes can occur in other conditions.

How Pregnancy Is Confirmed

Because Ladin sign is only a probable sign, additional testing is required to confirm pregnancy:

  • Detection of human chorionic gonadotropin (hCG) through a pregnancy test
  • Ultrasound, which provides positive evidence of pregnancy

NCLEX Tip

  • Presumptive signs = felt by the patient
  • Probable signs = observed by the examiner
  • Positive signs = confirmation of pregnancy
  • Ladin sign = Probable sign of pregnancy

Maternity Nursing Study Guide

Save Time Studying and Actually Learn
Nurse Sarah’s Maternity Nursing Study Notes are designed to help you study faster, remember more, and stress less. With 151 pages of simplified summaries, illustrations, mnemonics, and visual breakdowns, you’ll breeze through even the trickiest OB topics.

Laser-Focused on What You’ll See on Exams
Whether you’re prepping for nursing school exams or the NCLEX®, these notes focus on the exact maternity/OB concepts you’re most likely to be tested on with no filler, no wasted time.

Memory Hacks, Visuals & Rationales That Make It Stick
Colorful illustrations and proven mnemonics help you actually retain the material, while 220 practice questions with in-depth rationales teach you the “why” behind the right answers so that you’re not just memorizing, you’re understanding.

Available at: NurseSarah.com and Amazon.com* (This is an affiliate link. We may earn a small commission if you make a purchase through this link at no extra cost to you).

You may be interested in: Presumptive, Probable, Positive Pregnancy Sign Quiz

Please Share:

  • Print (Opens in new window) Print
  • Share on Facebook (Opens in new window) Facebook
  • Share on X (Opens in new window) X
  • Share on Pinterest (Opens in new window) Pinterest
  • More
  • Share on Reddit (Opens in new window) Reddit
  • Share on LinkedIn (Opens in new window) LinkedIn
  • Share on WhatsApp (Opens in new window) WhatsApp
  • Share on Telegram (Opens in new window) Telegram

Nursing Notes

Nursing School Bundles Notes by Nurse Sarah

RSS Latest YouTube Videos

  • Blood Collection Tubes Explained | Phlebotomy Lab Tube Anatomy
  • Nursing School Graduation Spring 2026: Congratulations!!
  • Top Blood Draw Mistakes Nurses & Phlebotomists Make
  • ECG EKG Interpretation Study Guide & Workbook for Nursing School Students

Recent Posts

  • Top 5 Early Pregnancy Signs to Know (Eponymous) for Maternity Exams
  • Piskacek’s Sign (Early Pregnancy Sign) Nursing Maternity Review
  • Ladin’s Sign (Early Pregnancy Sign) Nursing Maternity Review
  • Hegar’s Sign (Early Pregnancy) Nursing Maternity Review
  • Goodell’s Sign (Early Pregnancy) Nursing Maternity Review

Disclosure and Privacy Policy

This website provides entertainment value only, not medical advice or nursing protocols. We strive for 100% accuracy, but nursing procedures and state laws are constantly changing. By accessing any content on this site or its related media channels, you agree never to hold us liable for damages, harm, loss, or misinformation. See our full disclosure and privacy policy.

Important Links

  • Advertise
  • Contact Us

Follow Us on Social Media

  • Facebook Nursing
  • Instagram Nursing
  • TikTok Nurse
  • Twitter Nursing
  • YouTube Nursing

Copyright Notice

All images, articles, text, videos, and other content found on this website are protected by copyright law and are the intellectual property of RegisteredNurseRN.com or their respective owners.

Copyright © 2026 RegisteredNurseRN.com. All Rights Reserved.