Skeletal muscle tissue quiz for anatomy. There are three types of muscle tissue found in the human body: skeletal, cardiac, and smooth muscle tissue. In this skeletal muscle quiz, you can test you knowledge on the major structures that make up skeletal muscle tissue.
Before taking this quiz, you might want to review the skeletal muscle tissue anatomy notes, or watch the skeletal muscle YouTube video.
Skeletal Muscle Tissue Quiz for Anatomy

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Skeletal Muscle Tissue Quiz for Anatomy
1. The layer of connective tissue that surrounds the entire skeletal muscle organ, as pictured in figure 1, is called:
a. Perimysium
b. Epimysium
c. Endomysium
d. Myofibril
The answer is b, epimysium. This connective tissue layer surrounds the entire muscle organ. The prefix epi means upon, just like the epidermis is the outermost later upon the skin.
2. A bundle of several skeletal muscle fibers, as pictured in figure 2, is called:
a. Sarcomere
b. Myofibril
c. Fascicle
d. Muscle cell
The answer is c, fascicle. Fascicles consist of several muscle fibers that are surrounded by connective tissue called perimysium. The word fascicle means bundle.
3. The connective tissue surrounding each fascicle, as pictured in figure 3, is called:
a. Perimysium
b. Epimysium
c. Endomysium
d. Thick myosin filament
The answer is a, perimysium. This connective tissue is around each fascicle. The prefix peri means around.
4. The connective tissue that surrounds the individual skeletal muscle fibers, as pictured in figure 4, is called:
a. Perimysium
b. Endomysium
c. Epimysium
d. Myofibril
The answer is b, endomysium. Endo means within, and this is the connective tissue within each fascicle that surrounds the individual muscle fiber.
5. Skeletal muscle fibers are also surrounded by a cell membrane called:
a. Sarcolemma
b. Myofibril
c. Sarcomere
d. Myosin
The answer is a, sarcolemma. This is the thin cell membrane that surrounds the muscle fiber.
6. Skeletal muscle fibers are made up of tiny rods, as pictured in figure 5, called:
a. Sarcolemma
b. Endomysium
c. Perimysium
d. Myofibrils
The answer is d, myofibrils. The muscle fibers are made up of many of these myofibril rods, which consist of repeating segments called sarcomeres.
7. The unit responsible for skeletal muscle contraction, which repeats in segments within the myofibril, is called a sarcomere:
a. True
b. False
The answer is a, true. Sarcomeres are the units responsible for contraction. They contain myofilaments that slide past one another.
8. Skeletal muscle fibers contain only one nucleus in the center.
a. True
b. False
The answer is b, false. Skeletal muscle fibers contain many nuclei, and they appear around the peripheral portion of the muscle fiber.
9. Skeletal muscle fibers contain striations, which are light and dark bands (or stripes).
a. True
b. False
The answer is a, true. The light and dark bands are created by the different filaments within the sarcomere. Myosin is thick and creates a darker band, whereas actin is thin and forms a lighter band.
10. What is the zigzag portion called that forms the boundary ends of each sarcomere?
a. Z disc or Z line
b. Titin
c. M line
d. H zone
The answer is a, Z disc, also called a Z line. The Z disc marks the boundary of each sarcomere and allows for the attachment of actin filaments and titin.
11. Within each sarcomere, contraction occurs when thin (actin) filaments are grabbed by thick (myosin) filaments and pulled toward the center of each sarcomere.
a. True
b. False
The answer is a, true. This is called the sliding filament theory, and it describes how skeletal muscles contract via the many repeating sarcomere units that make up each myofibril.
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